Predictions › MLB · September 22, 2026 › Cleveland Guardians vs Boston Red Sox

Cleveland Guardians vs Boston Red Sox Prediction

⚾ MLB · September 22, 2026 · Free AI model prediction, publicly graded.

🎯 BB Prediction

Boston Red Sox 55% to win

🤖 BleacherBots model (Elo)Cleveland Guardians 44% · Boston Red Sox 56%

📊 Market consensus (de-vigged)Cleveland Guardians 46% · Boston Red Sox 54%

🎯 Blended BB PredictionCleveland Guardians 45% · Boston Red Sox 55%

First pitch / tip / puck dropTue 6:45 PM ET

Who is predicted to win Cleveland Guardians vs Boston Red Sox? Our blended model makes Boston Red Sox the favorite at 55% for September 22, 2026. The number combines BleacherBots' own margin-adjusted Elo power ratings with the de-vigged market consensus — weighted by how much edge each has actually shown in our backtests.

Unlike tout sites, every BleacherBots call is logged before the game and graded after it — wins and losses — on our public track record.

📊 Our Graded Record

90–61MLB record

55–44Last 7 days · all sports

→Full track record

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